Dissemination Multi-Drug and Carbapenems Resistant Pseudomonas aeruginosa among Clinical Isolates in Najaf Hospitals

Authors

  • Alaa Abdulhussein Rasool university of Kufa/College of Medicine
  • Ali M. Almohana university of Kufa/ College of Medicine

DOI:

https://doi.org/10.36320/ajb/v9.i3.7911

Keywords:

Pseudomonas aeruginosa, Antibiotic, Resistance, carbapenems

Abstract

Background:  Pseudomonas aeruginosa is one of the most common Gram negative pathogens associated with nosocomial infections. Carbapenems, specially imipenem and meropenem have the widest activity ranges of any β-lactam antibiotics and are often the most appropriate agents for use in the treatment of infections caused by multi-drug resistant P. aeruginosa. Resistance to carbapenems is emerging, and it is a great problem to therapeutic the serious infections caused by this bacteria.

Downloads

Download data is not yet available.

References

Gailienė, G.; Pavilonis, A. and Kareivienė, V.(2007). The peculiarities of Pseudomonas aeruginosa resistance to antibiotics and prevalence of serogroups. Medicina (Kaunas)., 43(1).36-42.

Švedienė, S. and Ivaškevičius, J.( 2006). Actualities of adults’ ventilator-associated pneumonia. Medicina (Kaunas).,42(2):91-7.

Flaws, M.L. and Moore N.M.(2011).Epidemiology and pathogenesis of Pseudomonas aeruginosa infections. Clin. Lab. Science. 24.1:p43.

Tellado, J.M. and Wilson, S.E.( 2005). Empiric treatment of nosocomial intra-abdominal infections: a focus on the carbapenems. Surg Infect (Larchmt);6(3):329-43.

Manchanda, V. Sanchaita, S. and Singh, N.P. (2010). “Multidrug resistant Acinetobacter.” J. of Glob. Infect. Dis., 2.3: 291–304. PMC. Web. 3 Jan. 2015.

Colandyn, F.( 2005).Appropriate and timely empirical antimicrobial treatment of ICU infections – a role for carbapenems. Acta. Clin. Belg.,60(2):51-62.

Riera, E.; Cabot, G.; Mulet, X. Garcı´a-Castillo, M.; del Campo,R..; Juan, C.; Canto´n, R. and Oliver, A. (2011). Pseudomonas aeruginosa carbapenem resistance mechanisms in Spain: impact on the activity of imipenem, meropenem and doripenem. J. Antimicrob. Chemother., 66(9):2022-7

Vitkauskienė, A.; Skrodenienė, E.; Dambrauskienė, A.; Bakšytė, G.; Macas, A. and Sakalauskas, R. (2011). Characteristics of Carbapenem-Resistant Pseudomonas aeruginosa Strains in Patients with Ventilator-Associated Pneumonia in Intensive Care Units. Medicina (Kaunas);47(12):652-6

Rodríguez-Martínez, J.M.; Poirel, L. and Nordmann P.(2009). Molecular Epidemiology and Mechanisms of Carbapenem Resistance in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. , 53 (11) 4783-4788 9.

Krisztina, M.; Wallace, P.; Endimiani, A. Taracila, M. A and Bonomo R.A.(2011).Carbapenems: Past, Present, and Future. Antimicrob. Agents Chemother.,55, (11):4943 4960.

Clinical and Laboratory Standards Institute (CLSI). (2013). Performance standards for antimicrobial susceptibility testing; 23ed. Informational Supplement.

Gales, A.C.; Reis, A.O. and Jones, R.N. (2001). Contemporary assessment of antimicrobial susceptibility testing methods for polymyxin B and colistin: review of available interpretative criteria and quality control guidelines. J. Clin. Microbiol., 39(1):183–190.

Yan, J.J. ;Tsai, S.H.; Chuang, C.L. and Wu, J. J.(2005). OXA-type beta-lactamases among extended-spectrum cephalosporin-resistant Pseudomonas aeruginosa isolates in a university hospital in southern Taiwan. J. Microbiol. Immunol. Infect., 39:130-134

Al-Muhannak, F.H. (2010). Spread of some extended-spectrum beta-lactamases in clinical isolates of Gram-negative bacilli in Najaf. M.Sc. Thesis. College of Medicine. University of Kufa.

Belal, E.J.K. (2010). Investigation of some β-lactamases in clinical isolates of Pseudomonas aeruginosa in Najaf City. M.Sc. Thesis. Education of Girls/ University of Kufa. Iraq.

Al-Shara, J.M.R. (2013). Phenotypic and molecular detecting of carbapenem resistant Pseudomonas aeruginosa in Najaf Hospitals. Ph.D. Thesis. Faculty of Science. University of Kufa. Iraq.

Al-Janabi, W. M. S.(2011). Bacteriological and histopathological study of patients with transitional cell carcinoma of urinary bladder in Al-Diwaniyah city/ Iraq. M.Sc. Thesis. College of Medicine. Al-Qadisiya University.

Saleh, R.H.(2012). Immunological and molecular study on Pseudomonas aeruginosa isolated from clinical samples in Babylon province. thesis in Microbiology. College of Medicine. Babylon University.

Abdul-Wahid, A.A.(2014). Dissemination of Aminoglycosides resistance in Pseudomonas aeruginosa isolates in Al-Nasseryia hospitals. M.Sc. Thesis. College of Medicine. University of Kufa. Iraq.

Aouf, A. (2001). Bacteriological and molecular study of Pseudomonas aeruginosa producing Elatase. M.Sc. Thesis. University of Kufa. Iraq.

Al-Nessani , A.L.S.(2011). Isolation and identification of Pseudomonas aeruginosa and determination of some virulence factors using specific genetic Markers .Ms.c. Thesis. Biology department .College of Science. Tikrit University .

Al-Kaabi, M.H.A. (2011). Detection of bla TEM, bla SHV, CTX-M-1 and CTX-M-ΙΙΙ genes by using Polymerase Chain Reaction technique from some Gram negative bacteria. M.Sc. Thesis. College of Science .Al-Mustansiryah University.

Al-Dahmoshi, H. O. M.(2013). Genotypic and phenotypic investigation of alginate biofilm formation among Pseudomonas aeruginosa isolated from burn victims in Babylon, Iraq. Babylon University, Science Faculty-Biology Department, Iraq.

Aghazadeh, M.; Hojabri, Z.; Mahdian, R.; Nahaei, M.R.; Rahmati, M.; Hojabri, T.; Pirzadeh, T. and Pajand, O. (2014). Role of efflux pumps: MexAB-OprM and MexXY (-OprA), AmpC cephalosporinase and OprD porin in non-metallo-β-lactamase producing Pseudomonas aeruginosa isolated from cystic fibrosis and burn patients. Infection, Genetics and Evolution. 24:187-192.

El-Gamal, M.I. and Oh C.H.(2010). Current status of carbapenem antibiotics. Curr. Top. Med. Chem.,10:1882-97.

Fayroz-Ali, J.M.H. (2012). Detection of quinolone resistance genes in Escherichia coli isolated from patients with significant bacteriuria in Najaf Province. Ph.D. Thesis. Sc. University of Babylon. Iraq.

Davies, T.A.; Shang, W.; Bush, K. et al.(2008). Affinity of doripenem and comparators to penicillin-binding proteins of Escherichia coli and Pseudomonas aeruginosa. Antimicrob Agents Chemother ., 52: 1510–2.

Mushtaq, S.; Ge, Y. and Livermore, D.M.( 2004). Doripenem versus Pseudomonas aeruginosa in vitro: activity against characterized isolates, mutants, and transconjugants and resistance selection potential. Antimicrob Agents Chemother.,; 48: 3086–92.

Al-Sehlawi, Z.S.R. (2012). Occurrence and characterization of AmpC β-lactamases in Klebsiella pneumoniae isolated from some medical centers in Najaf. Ph.D. Thesis. Sc., University of Babylon. Iraq.

Al-Delaimi, M.S. (2012). Antimicrobial activity of black seed oil and water extracts on multidrug resistant Pseudomonas aeruginosa. J. of university of Anbar for pure science. 6(3).

Downloads

Published

2017-07-10

How to Cite

Abdulhussein Rasool, A., & M. Almohana, A. (2017). Dissemination Multi-Drug and Carbapenems Resistant Pseudomonas aeruginosa among Clinical Isolates in Najaf Hospitals. Al-Kufa University Journal for Biology, 9(3), 119–128. https://doi.org/10.36320/ajb/v9.i3.7911

Similar Articles

1 2 3 4 5 6 7 8 9 > >> 

You may also start an advanced similarity search for this article.