Dissemination Multi-Drug and Carbapenems Resistant Pseudomonas aeruginosa among Clinical Isolates in Najaf Hospitals
DOI:
https://doi.org/10.36320/ajb/v9.i3.7911Keywords:
Pseudomonas aeruginosa, Antibiotic, Resistance, carbapenemsAbstract
Background: Pseudomonas aeruginosa is one of the most common Gram negative pathogens associated with nosocomial infections. Carbapenems, specially imipenem and meropenem have the widest activity ranges of any β-lactam antibiotics and are often the most appropriate agents for use in the treatment of infections caused by multi-drug resistant P. aeruginosa. Resistance to carbapenems is emerging, and it is a great problem to therapeutic the serious infections caused by this bacteria.
Downloads
References
Gailienė, G.; Pavilonis, A. and Kareivienė, V.(2007). The peculiarities of Pseudomonas aeruginosa resistance to antibiotics and prevalence of serogroups. Medicina (Kaunas)., 43(1).36-42.
Švedienė, S. and Ivaškevičius, J.( 2006). Actualities of adults’ ventilator-associated pneumonia. Medicina (Kaunas).,42(2):91-7.
Flaws, M.L. and Moore N.M.(2011).Epidemiology and pathogenesis of Pseudomonas aeruginosa infections. Clin. Lab. Science. 24.1:p43.
Tellado, J.M. and Wilson, S.E.( 2005). Empiric treatment of nosocomial intra-abdominal infections: a focus on the carbapenems. Surg Infect (Larchmt);6(3):329-43.
Manchanda, V. Sanchaita, S. and Singh, N.P. (2010). “Multidrug resistant Acinetobacter.” J. of Glob. Infect. Dis., 2.3: 291–304. PMC. Web. 3 Jan. 2015.
Colandyn, F.( 2005).Appropriate and timely empirical antimicrobial treatment of ICU infections – a role for carbapenems. Acta. Clin. Belg.,60(2):51-62.
Riera, E.; Cabot, G.; Mulet, X. Garcı´a-Castillo, M.; del Campo,R..; Juan, C.; Canto´n, R. and Oliver, A. (2011). Pseudomonas aeruginosa carbapenem resistance mechanisms in Spain: impact on the activity of imipenem, meropenem and doripenem. J. Antimicrob. Chemother., 66(9):2022-7
Vitkauskienė, A.; Skrodenienė, E.; Dambrauskienė, A.; Bakšytė, G.; Macas, A. and Sakalauskas, R. (2011). Characteristics of Carbapenem-Resistant Pseudomonas aeruginosa Strains in Patients with Ventilator-Associated Pneumonia in Intensive Care Units. Medicina (Kaunas);47(12):652-6
Rodríguez-Martínez, J.M.; Poirel, L. and Nordmann P.(2009). Molecular Epidemiology and Mechanisms of Carbapenem Resistance in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. , 53 (11) 4783-4788 9.
Krisztina, M.; Wallace, P.; Endimiani, A. Taracila, M. A and Bonomo R.A.(2011).Carbapenems: Past, Present, and Future. Antimicrob. Agents Chemother.,55, (11):4943 4960.
Clinical and Laboratory Standards Institute (CLSI). (2013). Performance standards for antimicrobial susceptibility testing; 23ed. Informational Supplement.
Gales, A.C.; Reis, A.O. and Jones, R.N. (2001). Contemporary assessment of antimicrobial susceptibility testing methods for polymyxin B and colistin: review of available interpretative criteria and quality control guidelines. J. Clin. Microbiol., 39(1):183–190.
Yan, J.J. ;Tsai, S.H.; Chuang, C.L. and Wu, J. J.(2005). OXA-type beta-lactamases among extended-spectrum cephalosporin-resistant Pseudomonas aeruginosa isolates in a university hospital in southern Taiwan. J. Microbiol. Immunol. Infect., 39:130-134
Al-Muhannak, F.H. (2010). Spread of some extended-spectrum beta-lactamases in clinical isolates of Gram-negative bacilli in Najaf. M.Sc. Thesis. College of Medicine. University of Kufa.
Belal, E.J.K. (2010). Investigation of some β-lactamases in clinical isolates of Pseudomonas aeruginosa in Najaf City. M.Sc. Thesis. Education of Girls/ University of Kufa. Iraq.
Al-Shara, J.M.R. (2013). Phenotypic and molecular detecting of carbapenem resistant Pseudomonas aeruginosa in Najaf Hospitals. Ph.D. Thesis. Faculty of Science. University of Kufa. Iraq.
Al-Janabi, W. M. S.(2011). Bacteriological and histopathological study of patients with transitional cell carcinoma of urinary bladder in Al-Diwaniyah city/ Iraq. M.Sc. Thesis. College of Medicine. Al-Qadisiya University.
Saleh, R.H.(2012). Immunological and molecular study on Pseudomonas aeruginosa isolated from clinical samples in Babylon province. thesis in Microbiology. College of Medicine. Babylon University.
Abdul-Wahid, A.A.(2014). Dissemination of Aminoglycosides resistance in Pseudomonas aeruginosa isolates in Al-Nasseryia hospitals. M.Sc. Thesis. College of Medicine. University of Kufa. Iraq.
Aouf, A. (2001). Bacteriological and molecular study of Pseudomonas aeruginosa producing Elatase. M.Sc. Thesis. University of Kufa. Iraq.
Al-Nessani , A.L.S.(2011). Isolation and identification of Pseudomonas aeruginosa and determination of some virulence factors using specific genetic Markers .Ms.c. Thesis. Biology department .College of Science. Tikrit University .
Al-Kaabi, M.H.A. (2011). Detection of bla TEM, bla SHV, CTX-M-1 and CTX-M-ΙΙΙ genes by using Polymerase Chain Reaction technique from some Gram negative bacteria. M.Sc. Thesis. College of Science .Al-Mustansiryah University.
Al-Dahmoshi, H. O. M.(2013). Genotypic and phenotypic investigation of alginate biofilm formation among Pseudomonas aeruginosa isolated from burn victims in Babylon, Iraq. Babylon University, Science Faculty-Biology Department, Iraq.
Aghazadeh, M.; Hojabri, Z.; Mahdian, R.; Nahaei, M.R.; Rahmati, M.; Hojabri, T.; Pirzadeh, T. and Pajand, O. (2014). Role of efflux pumps: MexAB-OprM and MexXY (-OprA), AmpC cephalosporinase and OprD porin in non-metallo-β-lactamase producing Pseudomonas aeruginosa isolated from cystic fibrosis and burn patients. Infection, Genetics and Evolution. 24:187-192.
El-Gamal, M.I. and Oh C.H.(2010). Current status of carbapenem antibiotics. Curr. Top. Med. Chem.,10:1882-97.
Fayroz-Ali, J.M.H. (2012). Detection of quinolone resistance genes in Escherichia coli isolated from patients with significant bacteriuria in Najaf Province. Ph.D. Thesis. Sc. University of Babylon. Iraq.
Davies, T.A.; Shang, W.; Bush, K. et al.(2008). Affinity of doripenem and comparators to penicillin-binding proteins of Escherichia coli and Pseudomonas aeruginosa. Antimicrob Agents Chemother ., 52: 1510–2.
Mushtaq, S.; Ge, Y. and Livermore, D.M.( 2004). Doripenem versus Pseudomonas aeruginosa in vitro: activity against characterized isolates, mutants, and transconjugants and resistance selection potential. Antimicrob Agents Chemother.,; 48: 3086–92.
Al-Sehlawi, Z.S.R. (2012). Occurrence and characterization of AmpC β-lactamases in Klebsiella pneumoniae isolated from some medical centers in Najaf. Ph.D. Thesis. Sc., University of Babylon. Iraq.
Al-Delaimi, M.S. (2012). Antimicrobial activity of black seed oil and water extracts on multidrug resistant Pseudomonas aeruginosa. J. of university of Anbar for pure science. 6(3).
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2017 Alaa Abdulhussein Rasool, Ali M. Almohana
This work is licensed under a Creative Commons Attribution 4.0 International License.
which allows users to copy, create extracts, abstracts, and new works from the Article, alter and revise the Article, and make commercial use of the Article (including reuse and/or resale of the Article by commercial entities), provided the user gives appropriate credit (with a link to the formal publication through the relevant DOI), provides a link to the license, indicates if changes were made and the licensor is not represented as endorsing the use made of the work.