Effect of adiponectin on T2DM and its correlation with IR in Iraqi Arabic population

Authors

  • Majid Kadhum Hussein Department of biochemistry, Faculty of medicine ,University of Kufa, Iraq
  • Asia Ali Hamza Department of biochemistry, Faculty of medicine ,University of Kufa, Iraq
  • Ali Abdulzahra Ahmed Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Kufa, Iraq

DOI:

https://doi.org/10.36320/ajb/v12.i3.11794

Keywords:

overweight, Insulin resistance, adiponectin, T2DM

Abstract

Adiponectin is a cytokine released from adipose tissue and may have an influence on many metabolic pathways, including insulin resistance and T2DM.

 Aim: To find the relationship between adiponectin and IR and its effect on glucose level in T2DM patients in Iraqi population.

 Method: This study has a two hundred participants (control) and another two hundred T2DM patients. The affirming of T2DM was introduced following criteria of WHO. FBG and HOMA-IR were also measured.

 Results: A significant correlation between IR and T2DM with a significant reciprocal relationship between adiponectin level HOMA-IR.

Conclusion: The present study clarifies that T2DM patients have a significant low level of adiponectin. Adiponectin has a glucose and IR lowering effect as low level of adiponectin is associated with increased IR and hyperglycemia

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References

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Published

2020-09-01

How to Cite

Kadhum Hussein, M., Ali Hamza, A., & Abdulzahra Ahmed, A. (2020). Effect of adiponectin on T2DM and its correlation with IR in Iraqi Arabic population. Al-Kufa University Journal for Biology, 12(3), 25–28. https://doi.org/10.36320/ajb/v12.i3.11794

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